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  • Dept. of Pharmacology, JIPMER 59. f Formula: AUC = [ (c1+c2)X ( {t2-t1}/2)]+ [ (c2+c3)X ( {t3-t2}/2)]…………+. [ (cn+cn+1)X ( {tn+1-tn}/2)] where c = concentration in µ g and t = corresponding time in min. AUC is. expressed as µ g/ml/min.
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  • In clinical pharmacology, experiments are conducted to investigate both pharmacokinetic and pharmacodynamic properties of a drug. Pharmacokinetics describes the rate of drug absorption and other processes involved in its distribution, metabolism and elimination.

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